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A Versatile RNA Vector for Delivery of Coding and Noncoding RNAs

The discovery that RNA viruses, lacking any DNA intermediate, can be engineered to express both coding and noncoding RNAs suggests that this platform may have therapeutic value as a delivery vehicle. Here we illustrate that a self-replicating, noninfectious RNA, modeled on influenza virus, provides...

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Detalles Bibliográficos
Main Authors: Schmid, Sonja, Zony, Lum C., tenOever, Benjamin R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911536/
https://ncbi.nlm.nih.gov/pubmed/24307584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03267-13
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