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A Versatile RNA Vector for Delivery of Coding and Noncoding RNAs

The discovery that RNA viruses, lacking any DNA intermediate, can be engineered to express both coding and noncoding RNAs suggests that this platform may have therapeutic value as a delivery vehicle. Here we illustrate that a self-replicating, noninfectious RNA, modeled on influenza virus, provides...

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Detalhes bibliográficos
Main Authors: Schmid, Sonja, Zony, Lum C., tenOever, Benjamin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911536/
https://ncbi.nlm.nih.gov/pubmed/24307584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03267-13
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