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Mapping the protein–protein and genetic interactions of cancer to guide precision medicine

Massive efforts to sequence cancer genomes have compiled an impressive catalogue of cancer mutations, revealing the recurrent exploitation of a handful of ‘hallmark cancer pathways’. However, unraveling how sets of mutated proteins in these and other pathways hijack pro-proliferative signaling netwo...

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Dades bibliogràfiques
Publicat a:Curr Opin Genet Dev
Autors principals: Bouhaddou, Mehdi, Eckhardt, Manon, Naing, Zun Zar Chi, Kim, Minkyu, Ideker, Trey, Krogan, Nevan J
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746583/
https://ncbi.nlm.nih.gov/pubmed/31288129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2019.04.005
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