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Mapping the protein–protein and genetic interactions of cancer to guide precision medicine

Massive efforts to sequence cancer genomes have compiled an impressive catalogue of cancer mutations, revealing the recurrent exploitation of a handful of ‘hallmark cancer pathways’. However, unraveling how sets of mutated proteins in these and other pathways hijack pro-proliferative signaling netwo...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Bouhaddou, Mehdi, Eckhardt, Manon, Naing, Zun Zar Chi, Kim, Minkyu, Ideker, Trey, Krogan, Nevan J
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746583/
https://ncbi.nlm.nih.gov/pubmed/31288129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2019.04.005
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