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Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes

This work demonstrates how gene association studies can be analyzed to map a global landscape of genetic interactions among protein complexes and pathways. Despite the immense potential of gene association studies, they have been challenging to analyze because most traits are complex, involving the...

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Détails bibliographiques
Auteurs principaux: Hannum, Gregory, Srivas, Rohith, Guénolé, Aude, van Attikum, Haico, Krogan, Nevan J., Karp, Richard M., Ideker, Trey
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788232/
https://ncbi.nlm.nih.gov/pubmed/20041197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000782
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