Improved functional overview of protein complexes using inferred epistatic relationships

BACKGROUND: Epistatic Miniarray Profiling(E-MAP) quantifies the net effect on growth rate of disrupting pairs of genes, often producing phenotypes that may be more (negative epistasis) or less (positive epistasis) severe than the phenotype predicted based on single gene disruptions. Epistatic intera...

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Hlavní autoři: Ryan, Colm, Greene, Derek, Guénolé, Aude, van Attikum, Haico, Krogan, Nevan J, Cunningham, Pádraig, Cagney, Gerard
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117733/
https://ncbi.nlm.nih.gov/pubmed/21605386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-80
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