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All or Nothing: Protein Complexes Flip Essentiality between Distantly Related Eukaryotes

In the budding yeast Saccharomyces cerevisiae, the subunits of any given protein complex are either mostly essential or mostly nonessential, suggesting that essentiality is a property of molecular machines rather than individual components. There are exceptions to this rule, however, that is, noness...

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Detalhes bibliográficos
Main Authors: Ryan, Colm J., Krogan, Nevan J., Cunningham, Pádraig, Cagney, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698920/
https://ncbi.nlm.nih.gov/pubmed/23661563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evt074
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