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Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs

BACKGROUND: Gene and protein interactions are commonly represented as networks, with the genes or proteins comprising the nodes and the relationship between them as edges. Motifs, or small local configurations of edges and nodes that arise repeatedly, can be used to simplify the interpretation of ne...

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Autori principali: Casey, Fergal, Krogan, Nevan, Shields, Denis C, Cagney, Gerard
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176491/
https://ncbi.nlm.nih.gov/pubmed/21859460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-133
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