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Optimal stepwise experimental design for pairwise functional interaction studies

Motivation: Pairwise experimental perturbation is increasingly used to probe gene and protein function because these studies offer powerful insight into the activity and regulation of biological systems. Symmetric two-dimensional datasets, such as pairwise genetic interactions are amenable to an opt...

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Detalhes bibliográficos
Main Authors: Casey, Fergal P., Cagney, Gerard, Krogan, Nevan J., Shields, Denis C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493128/
https://ncbi.nlm.nih.gov/pubmed/18805797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn472
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