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Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs

BACKGROUND: Gene and protein interactions are commonly represented as networks, with the genes or proteins comprising the nodes and the relationship between them as edges. Motifs, or small local configurations of edges and nodes that arise repeatedly, can be used to simplify the interpretation of ne...

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Bibliographic Details
Main Authors: Casey, Fergal, Krogan, Nevan, Shields, Denis C, Cagney, Gerard
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176491/
https://ncbi.nlm.nih.gov/pubmed/21859460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-133
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