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Improved functional overview of protein complexes using inferred epistatic relationships

BACKGROUND: Epistatic Miniarray Profiling(E-MAP) quantifies the net effect on growth rate of disrupting pairs of genes, often producing phenotypes that may be more (negative epistasis) or less (positive epistasis) severe than the phenotype predicted based on single gene disruptions. Epistatic intera...

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Autors principals: Ryan, Colm, Greene, Derek, Guénolé, Aude, van Attikum, Haico, Krogan, Nevan J, Cunningham, Pádraig, Cagney, Gerard
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117733/
https://ncbi.nlm.nih.gov/pubmed/21605386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-80
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