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Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes

This work demonstrates how gene association studies can be analyzed to map a global landscape of genetic interactions among protein complexes and pathways. Despite the immense potential of gene association studies, they have been challenging to analyze because most traits are complex, involving the...

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Detalles Bibliográficos
Autores principales: Hannum, Gregory, Srivas, Rohith, Guénolé, Aude, van Attikum, Haico, Krogan, Nevan J., Karp, Richard M., Ideker, Trey
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788232/
https://ncbi.nlm.nih.gov/pubmed/20041197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000782
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