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Dissection of DNA Damage Responses Using Multiconditional Genetic Interaction Maps

To protect the genome, cells have evolved a diverse set of pathways designed to sense, signal, and repair multiple types of DNA damage. To assess the degree of coordination and crosstalk among these pathways, we systematically mapped changes in the cell's genetic network across a panel of diffe...

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Detalhes bibliográficos
Main Authors: Guénolé, Aude, Srivas, Rohith, Vreeken, Kees, Wang, Ze Zhong, Wang, Shuyi, Krogan, Nevan J., Ideker, Trey, van Attikum, Haico
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633480/
https://ncbi.nlm.nih.gov/pubmed/23273983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.11.023
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