Dynamic cellular maps of molecular species: Application to drug-target interactions

Por García, Carolina, Losada, Alejandro, Sacristán, Miguel A., Martínez-Leal, Juan Fernando, Galmarini, Carlos M., Lillo, M. Pilar
Publicado no Sci Rep (2018)

Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival

Por Losada, Alejandro, Muñoz-Alonso, María José, Martínez-Díez, Marta, Gago, Federico, Domínguez, Juan Manuel, Martínez-Leal, Juan Fernando, Galmarini, Carlos M.
Publicado no Br J Cancer (2018)

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin

Por Losada, Alejandro, Muñoz-Alonso, María José, García, Carolina, Sánchez-Murcia, Pedro A., Martínez-Leal, Juan Fernando, Domínguez, Juan Manuel, Lillo, M. Pilar, Gago, Federico, Galmarini, Carlos M.
Publicado no Sci Rep (2016)

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

Por White, Kris M., Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B., Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M., Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M., Krogan, Nevan J., García-Sastre, Adolfo
Publicado no Science (2021)