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Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival
BACKGROUND: Through several not-fully-characterised moonlighting functions, translation elongation factor eEF1A2 is known to provide a fitness boost to cancer cells. Furthermore, eEF1A2 has been demonstrated to confer neoplastic characteristics on preneoplastic, nontumourigenic precursor cells. We h...
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Publicado en: | Br J Cancer |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Nature Publishing Group UK
2018
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6265344/ https://ncbi.nlm.nih.gov/pubmed/30420615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0336-y |
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