Cargando...

Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival

BACKGROUND: Through several not-fully-characterised moonlighting functions, translation elongation factor eEF1A2 is known to provide a fitness boost to cancer cells. Furthermore, eEF1A2 has been demonstrated to confer neoplastic characteristics on preneoplastic, nontumourigenic precursor cells. We h...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Br J Cancer
Main Authors: Losada, Alejandro, Muñoz-Alonso, María José, Martínez-Díez, Marta, Gago, Federico, Domínguez, Juan Manuel, Martínez-Leal, Juan Fernando, Galmarini, Carlos M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265344/
https://ncbi.nlm.nih.gov/pubmed/30420615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0336-y
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!