Development of Neutralizing Antibodies against Zika Virus Based on Its Envelope Protein Structure

por Yang, Chunpeng, Gong, Rui, de Val, Natalia
Publicado en Virol Sin (2019)

Model building and refinement of a natively glycosylated HIV-1 Env protein by high-resolution cryoEM

por Lee, Jeong Hyun, de Val, Natalia, Lyumkis, Dmitry, Ward, Andrew B.
Publicado en Structure (2015)

Well-Ordered Trimeric HIV-1 Subtype B and C Soluble Spike Mimetics Generated by Negative Selection Display Native-like Properties

por Guenaga, Javier, de Val, Natalia, Tran, Karen, Feng, Yu, Satchwell, Karen, Ward, Andrew B., Wyatt, Richard T.
Publicado en PLoS Pathog (2015)

Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers

por Guenaga, Javier, Dubrovskaya, Viktoriya, de Val, Natalia, Sharma, Shailendra K., Carrette, Barbara, Ward, Andrew B., Wyatt, Richard T.
Publicado en J Virol (2016)

Structures and operating principles of the replisome

por Gao, Yang, Cui, Yanxiang, Fox, Tara, Lin, Shiqiang, Wang, Huaibin, de Val, Natalia, Zhou, Z. Hong, Yang, Wei
Publicado en Science (2019)

Cryo-EM structure of the bacterial Ton motor subcomplex ExbB–ExbD provides information on structure and stoichiometry

por Celia, Herve, Botos, Istvan, Ni, Xiaodan, Fox, Tara, De Val, Natalia, Lloubes, Roland, Jiang, Jiansen, Buchanan, Susan K.
Publicado en Commun Biol (2019)

Author Correction: Cryo-EM structure of the bacterial Ton motor subcomplex ExbB–ExbD provides information on structure and stoichiometry

por Celia, Herve, Botos, Istvan, Ni, Xiaodan, Fox, Tara, de Val, Natalia, Lloubes, Roland, Jiang, Jiansen, Buchanan, Susan K.
Publicado en Commun Biol (2020)

Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins

por de Val, Natalia, McMurray, Michael A., Lam, Lisa H., Hsiung, Chris C.-S., Bertin, Aurélie, Nogales, Eva, Thorner, Jeremy
Publicado 2013

Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design

por Sharma, Shailendra Kumar, de Val, Natalia, Bale, Shridhar, Guenaga, Javier, Tran, Karen, Feng, Yu, Dubrovskaya, Viktoriya, Ward, Andrew B., Wyatt, Richard T.
Publicado en Cell Rep (2015)

Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms

por Zhou, Bing-Rui, Feng, Hanqiao, Kale, Seyit, Fox, Tara, Khant, Htet, de Val, Natalia, Ghirlando, Rodolfo, Panchenko, Anna R., Bai, Yawen
Publicado en Mol Cell (2020)

Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response

por Dubrovskaya, Viktoriya, Guenaga, Javier, de Val, Natalia, Wilson, Richard, Feng, Yu, Movsesyan, Arlette, Karlsson Hedestam, Gunilla B., Ward, Andrew B., Wyatt, Richard T.
Publicado en PLoS Pathog (2017)

Structure of an activated DNA-PK and its implications for NHEJ

por Chen, Xuemin, Xu, Xiang, Chen, Yun, Cheung, Joyce C., Wang, Huaibin, Jiang, Jiansen, de Val, Natalia, Fox, Tara, Gellert, Martin, Yang, Wei
Publicado en Mol Cell (2020)

Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage

por Yang, Lifei, Sharma, Shailendra Kumar, Cottrell, Christopher, Guenaga, Javier, Tran, Karen, Wilson, Richard, Behrens, Anna-Janina, Crispin, Max, de Val, Natalia, Wyatt, Richard T.
Publicado en Front Immunol (2018)

Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo

por Brooks, Matthew J., Chen, Holly Y., Kelley, Ryan A., Mondal, Anupam K., Nagashima, Kunio, De Val, Natalia, Li, Tiansen, Chaitankar, Vijender, Swaroop, Anand
Publicado en Stem Cell Reports (2019)

Cryo-EM reveals unanchored M1-ubiquitin chain binding at hRpn11 of the 26S proteasome

por Chen, Xiang, Dorris, Zachary, Shi, Dan, Huang, Rick K, Khant, Htet, Fox, Tara, de Val, Natalia, Williams, Dewight, Zhang, Ping, Walters, Kylie J
Publicado en Structure (2020)

Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein

por Guenaga, Javier, Garces, Fernando, de Val, Natalia, Stanfield, Robyn L., Dubrovskaya, Viktoriya, Higgins, Brett, Carrette, Barbara, Ward, Andrew B., Wilson, Ian A., Wyatt, Richard T.
Publicado en Immunity (2017)

Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies

por Feng, Yu, Tran, Karen, Bale, Shridhar, Kumar, Shailendra, Guenaga, Javier, Wilson, Richard, de Val, Natalia, Arendt, Heather, DeStefano, Joanne, Ward, Andrew B., Wyatt, Richard T.
Publicado en PLoS Pathog (2016)

Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery

por Botos, Istvan, Lountos, George T., Wu, Weimin, Cherry, Scott, Ghirlando, Rodolfo, Kudzhaev, Arsen M., Rotanova, Tatyana V., de Val, Natalia, Tropea, Joseph E., Gustchina, Alla, Wlodawer, Alexander
Publicado en Curr Res Struct Biol (2019)

Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation

por Yang, Shu, Gorshkov, Kirill, Lee, Emily M., Xu, Miao, Cheng, Yu-Shan, Sun, Nuo, Soheilian, Ferri, de Val, Natalia, Ming, Guoli, Song, Hongjun, Tang, Hengli, Zheng, Wei
Publicado en Front Microbiol (2020)

Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability

por Kong, Leopold, He, Linling, de Val, Natalia, Vora, Nemil, Morris, Charles D., Azadnia, Parisa, Sok, Devin, Zhou, Bin, Burton, Dennis R., Ward, Andrew B., Wilson, Ian A., Zhu, Jiang
Publicado en Nat Commun (2016)