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Model building and refinement of a natively glycosylated HIV-1 Env protein by high-resolution cryoEM
Secretory and membrane proteins from mammalian cells undergo post-translational modifications, including N-linked glycosylation, which can result in a large number of possible glycoforms. This sample heterogeneity can be problematic for structural studies, particularly X-ray crystallography. Thus, c...
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| Publicado no: | Structure |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618500/ https://ncbi.nlm.nih.gov/pubmed/26388028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.07.020 |
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