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CryoEM structure of a native, fully glycosylated and cleaved HIV-1 envelope trimer

The envelope glycoprotein trimer (Env) on the surface of HIV-1 recognizes CD4+ T cells and mediates viral entry. During this process, Env undergoes large conformational rearrangements making it difficult to study in its native state. Soluble, stabilized trimers have provided valuable insights into E...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Science
Egile Nagusiak: Lee, Jeong Hyun, Ozorowski, Gabriel, Ward, Andrew B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001164/
https://ncbi.nlm.nih.gov/pubmed/26941313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad2450
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