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CryoEM structure of a native, fully glycosylated and cleaved HIV-1 envelope trimer

The envelope glycoprotein trimer (Env) on the surface of HIV-1 recognizes CD4+ T cells and mediates viral entry. During this process, Env undergoes large conformational rearrangements making it difficult to study in its native state. Soluble, stabilized trimers have provided valuable insights into E...

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書目詳細資料
發表在:Science
Main Authors: Lee, Jeong Hyun, Ozorowski, Gabriel, Ward, Andrew B.
格式: Artigo
語言:Inglês
出版: 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001164/
https://ncbi.nlm.nih.gov/pubmed/26941313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad2450
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