Llwytho...

CryoEM structure of a native, fully glycosylated and cleaved HIV-1 envelope trimer

The envelope glycoprotein trimer (Env) on the surface of HIV-1 recognizes CD4+ T cells and mediates viral entry. During this process, Env undergoes large conformational rearrangements making it difficult to study in its native state. Soluble, stabilized trimers have provided valuable insights into E...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Science
Prif Awduron: Lee, Jeong Hyun, Ozorowski, Gabriel, Ward, Andrew B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001164/
https://ncbi.nlm.nih.gov/pubmed/26941313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad2450
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!