Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 Env trimer

The HIV-1 envelope glycoprotein (Env) trimer contains the receptor binding sites and membrane fusion machinery that introduce the viral genome into the host cell. As the only target for broadly neutralizing antibodies (bnAbs), Env is a focus for rational vaccine design. We present a cryo-electron mi...

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Detalhes bibliográficos
Main Authors: Lyumkis, Dmitry, Julien, Jean-Philippe, de Val, Natalia, Cupo, Albert, Potter, Clinton S., Klasse, Per Johan, Burton, Dennis R., Sanders, Rogier W., Moore, John P., Carragher, Bridget, Wilson, Ian A., Ward, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954647/
https://ncbi.nlm.nih.gov/pubmed/24179160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1245627
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