Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 Env trimer

The HIV-1 envelope glycoprotein (Env) trimer contains the receptor binding sites and membrane fusion machinery that introduce the viral genome into the host cell. As the only target for broadly neutralizing antibodies (bnAbs), Env is a focus for rational vaccine design. We present a cryo-electron mi...

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Bibliografiska uppgifter
Huvudupphovsmän: Lyumkis, Dmitry, Julien, Jean-Philippe, de Val, Natalia, Cupo, Albert, Potter, Clinton S., Klasse, Per Johan, Burton, Dennis R., Sanders, Rogier W., Moore, John P., Carragher, Bridget, Wilson, Ian A., Ward, Andrew B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954647/
https://ncbi.nlm.nih.gov/pubmed/24179160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1245627
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