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Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 Env trimer

The HIV-1 envelope glycoprotein (Env) trimer contains the receptor binding sites and membrane fusion machinery that introduce the viral genome into the host cell. As the only target for broadly neutralizing antibodies (bnAbs), Env is a focus for rational vaccine design. We present a cryo-electron mi...

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Detaylı Bibliyografya
Asıl Yazarlar: Lyumkis, Dmitry, Julien, Jean-Philippe, de Val, Natalia, Cupo, Albert, Potter, Clinton S., Klasse, Per Johan, Burton, Dennis R., Sanders, Rogier W., Moore, John P., Carragher, Bridget, Wilson, Ian A., Ward, Andrew B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954647/
https://ncbi.nlm.nih.gov/pubmed/24179160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1245627
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