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CryoEM structure of a native, fully glycosylated and cleaved HIV-1 envelope trimer
The envelope glycoprotein trimer (Env) on the surface of HIV-1 recognizes CD4+ T cells and mediates viral entry. During this process, Env undergoes large conformational rearrangements making it difficult to study in its native state. Soluble, stabilized trimers have provided valuable insights into E...
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| Publicado en: | Science |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001164/ https://ncbi.nlm.nih.gov/pubmed/26941313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad2450 |
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