Structure of a C-terminal AHNAK peptide in a 1:2:2 complex with S100A10 and an acetylated N-terminal peptide of annexin A2

Por Ozorowski, Gabriel, Milton, Saskia, Luecke, Hartmut
Publicado em 2013

CryoEM structure of a native, fully glycosylated and cleaved HIV-1 envelope trimer

Por Lee, Jeong Hyun, Ozorowski, Gabriel, Ward, Andrew B.
Publicado no Science (2016)

Env exceptionalism – Why are HIV-1 Env glycoproteins atypical immunogens?

Por Klasse, P. J., Ozorowski, Gabriel, Sanders, Rogier W., Moore, John P.
Publicado no Cell Host Microbe (2020)

A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide

Por Ozorowski, Gabriel, Torres, Jonathan L., Santos-Martins, Diogo, Forli, Stefano, Ward, Andrew B.
Publicado no Cell Rep (2020)

Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein

Por Ahmed, Shubbir, Shrivastava, Tripti, Kumar, Naresh, Ozorowski, Gabriel, Ward, Andrew B., Chakrabarti, Bimal K.
Publicado no J Biol Chem (2017)

Field-Based Affinity Optimization of a Novel Azabicyclohexane Scaffold HIV-1 Entry Inhibitor

Por Meuser, Megan E., Rashad, Adel A., Ozorowski, Gabriel, Dick, Alexej, Ward, Andrew B., Cocklin, Simon
Publicado no Molecules (2019)

A Transporter Converted into a Sensor, a Phototaxis Signaling Mutant of Bacteriorhodopsin at 3.0 Å

Por Spudich, Elena N., Ozorowski, Gabriel, Schow, Eric V., Tobias, Douglas J., Spudich, John L., Luecke, Hartmut
Publicado em 2011

Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer

Por Sliepen, Kwinten, van Montfort, Thijs, Ozorowski, Gabriel, Pritchard, Laura K., Crispin, Max, Ward, Andrew B., Sanders, Rogier W.
Publicado no Biomolecules (2015)

Characterization of a stable HIV-1 B/C recombinant, soluble, and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes

Por Kumar, Rajesh, Ozorowski, Gabriel, Kumar, Vivek, Holden, Lauren G., Shrivastava, Tripti, Patil, Shilpa, Deshpande, Suprit, Ward, Andrew B., Bhattacharya, Jayanta
Publicado no J Biol Chem (2017)

The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization

Por Lei, Lin, Yang, Yuhe R., Tran, Karen, Wang, Yimeng, Chiang, Chi-I, Ozorowski, Gabriel, Xiao, Yongli, Ward, Andrew B., Wyatt, Richard T., Li, Yuxing
Publicado no Cell Rep (2019)

High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers

Por Sullivan, Jonathan T., Sulli, Chidananda, Nilo, Alberto, Yasmeen, Anila, Ozorowski, Gabriel, Sanders, Rogier W., Ward, Andrew B., Klasse, P. J., Moore, John P., Doranz, Benjamin J.
Publicado no J Virol (2017)

Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro

Por Ozorowski, Gabriel, Cupo, Albert, Golabek, Michael, LoPiccolo, Michelle, Ketas, Thomas A., Cavallary, Matt, Cottrell, Christopher A., Klasse, P. J., Ward, Andrew B., Moore, John P.
Publicado no J Virol (2018)

Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity

Por Sliepen, Kwinten, Ozorowski, Gabriel, Burger, Judith A., van Montfort, Thijs, Stunnenberg, Melissa, LaBranche, Celia, Montefiori, David C., Moore, John P., Ward, Andrew B., Sanders, Rogier W.
Publicado no Retrovirology (2015)

Open and Closed Structures Reveal Allostery and Pliability in the HIV-1 Envelope Spike

Por Ozorowski, Gabriel, Pallesen, Jesper, de Val, Natalia, Lyumkis, Dmitry, Cottrell, Christopher A., Torres, Jonathan L., Copps, Jeffrey, Stanfield, Robyn L., Cupo, Albert, Pugach, Pavel, Moore, John P., Wilson, Ian A., Ward, Andrew B.
Publicado no Nature (2017)

Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer

Por He, Linling, Lin, Xiaohe, de Val, Natalia, Saye-Francisco, Karen L., Mann, Colin J., Augst, Ryan, Morris, Charles D., Azadnia, Parisa, Zhou, Bin, Sok, Devin, Ozorowski, Gabriel, Ward, Andrew B., Burton, Dennis R., Zhu, Jiang
Publicado no Front Immunol (2017)

Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers

Por Aldon, Yoann, McKay, Paul F., Allen, Joel, Ozorowski, Gabriel, Felfödiné Lévai, Réka, Tolazzi, Monica, Rogers, Paul, He, Linling, de Val, Natalia, Fábián, Katalin, Scarlatti, Gabriella, Zhu, Jiang, Ward, Andrew B., Crispin, Max, Shattock, Robin J.
Publicado no Cell Rep (2018)

Structural constraints determine the glycosylation of HIV-1 envelope trimers

Por Pritchard, Laura K., Vasiljevic, Snezana, Ozorowski, Gabriel, Seabright, Gemma E., Cupo, Albert, Ringe, Rajesh, Kim, Helen J., Sanders, Rogier W., Doores, Katie J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Moore, John P., Crispin, Max
Publicado no Cell Rep (2015)

Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

Por Yuan, Meng, Cottrell, Christopher A., Ozorowski, Gabriel, van Gils, Marit J., Kumar, Sonu, Wu, Nicholas C., Sarkar, Anita, Torres, Jonathan L., de Val, Natalia, Copps, Jeffrey, Moore, John P., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Publicado no Cell Host Microbe (2019)

Integrity of glycosylation processing of a glycan-depleted trimeric HIV-1 immunogen targeting key B-cell lineages

Por Behrens, Anna-Janina, Kumar, Abhinav, Medina-Ramirez, Max, Cupo, Albert, Marshall, Kevin, Portillo, Victor C., Harvey, David J., Ozorowski, Gabriel, Zitzmann, Nicole, Wilson, Ian A., Ward, Andrew B., Struwe, Weston B., Moore, John P., Sanders, Rogier W., Crispin, Max
Publicado no J Proteome Res (2018)

Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate...

Por Whitaker, Neal, Hickey, John M., Kaur, Kawaljit, Xiong, Jian, Sawant, Nishant, Cupo, Albert, Lee, Wen-Hsin, Ozorowski, Gabriel, Medina-Ramírez, Max, Ward, Andrew B., Sanders, Rogier W., Moore, John P., Joshi, Sangeeta B., Volkin, David B., Dey, Antu K.
Publicado no J Pharm Sci (2019)