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Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers
The HIV-1-envelope glycoprotein (Env) is the main target of antigen design for antibody-based prophylactic vaccines. The generation of broadly neutralizing antibodies (bNAb) likely requires the appropriate presentation of stabilized trimers preventing exposure of non-neutralizing antibody (nNAb) epi...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6167709/ https://ncbi.nlm.nih.gov/pubmed/30232012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.051 |
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