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Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer

Generation of a stable, soluble mimic of the HIV-1 envelope glycoprotein (Env) trimer on the virion surface has been considered an important first step for developing a successful HIV-1 vaccine. Recently, a soluble native-like Env trimer (BG505 SOSIP.664) has been described. This protein has facilit...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Sliepen, Kwinten, van Montfort, Thijs, Ozorowski, Gabriel, Pritchard, Laura K., Crispin, Max, Ward, Andrew B., Sanders, Rogier W.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693263/
https://ncbi.nlm.nih.gov/pubmed/26512709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5042919
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