Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

Major neutralizing antibody immune evasion strategies of the HIV-1 envelope glycoprotein (Env) trimer include conformational and structural instability. Stabilized soluble trimers such as BG505 SOSIP.664 mimic the structure of virion-associated Env but nevertheless sample different conformational st...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Schiffner, Torben, de Val, Natalia, Russell, Rebecca A., de Taeye, Steven W., de la Peña, Alba Torrents, Ozorowski, Gabriel, Kim, Helen J., Nieusma, Travis, Brod, Florian, Cupo, Albert, Sanders, Rogier W., Moore, John P., Ward, Andrew B., Sattentau, Quentin J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702668/
https://ncbi.nlm.nih.gov/pubmed/26512083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01942-15
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