A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide

著者: Ozorowski, Gabriel, Torres, Jonathan L., Santos-Martins, Diogo, Forli, Stefano, Ward, Andrew B.
出版年 Cell Rep (2020)

Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

著者: Oyen, David, Torres, Jonathan L., Cottrell, Christopher A., Richter King, C., Wilson, Ian A., Ward, Andrew B.
出版年 Sci Adv (2018)

SOS and IP Modifications Predominantly Affect the Yield but Not Other Properties of SOSIP.664 HIV-1 Env Glycoprotein Trimers

著者: Ringe, Rajesh P., Colin, Philippe, Torres, Jonathan L., Yasmeen, Anila, Lee, Wen-Hsin, Cupo, Albert, Ward, Andrew B., Klasse, P. J., Moore, John P.
出版年 J Virol (2019)

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

著者: Stanfield, Robyn L., Berndsen, Zachary T., Huang, Ruiqi, Sok, Devin, Warner, Gabrielle, Torres, Jonathan L., Burton, Dennis R., Ward, Andrew B., Wilson, Ian A., Smider, Vaughn V.
出版年 Sci Adv (2020)

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

著者: Torrents de la Peña, Alba, Rantalainen, Kimmo, Cottrell, Christopher A., Allen, Joel D., van Gils, Marit J., Torres, Jonathan L., Crispin, Max, Sanders, Rogier W., Ward, Andrew B.
出版年 PLoS Pathog (2019)

Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein

著者: Oyen, David, Torres, Jonathan L., Wille-Reece, Ulrike, Ockenhouse, Christian F., Emerling, Daniel, Glanville, Jacob, Volkmuth, Wayne, Flores-Garcia, Yevel, Zavala, Fidel, Ward, Andrew B., King, C. Richter, Wilson, Ian A.
出版年 Proc Natl Acad Sci U S A (2017)

Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design

著者: Rantalainen, Kimmo, Berndsen, Zachary T., Murrell, Sasha, Cao, Liwei, Omorodion, Oluwarotimi, Torres, Jonathan L., Wu, Mengyu, Umotoy, Jeffrey, Copps, Jeffrey, Poignard, Pascal, Landais, Elise, Paulson, James C., Wilson, Ian A., Ward, Andrew B.
出版年 Cell Rep (2018)

Open and Closed Structures Reveal Allostery and Pliability in the HIV-1 Envelope Spike

著者: Ozorowski, Gabriel, Pallesen, Jesper, de Val, Natalia, Lyumkis, Dmitry, Cottrell, Christopher A., Torres, Jonathan L., Copps, Jeffrey, Stanfield, Robyn L., Cupo, Albert, Pugach, Pavel, Moore, John P., Wilson, Ian A., Ward, Andrew B.
出版年 Nature (2017)

Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers

著者: Koch, Kathrin, Kalusche, Sarah, Torres, Jonathan L., Stanfield, Robyn L., Danquah, Welbeck, Khazanehdari, Kamal, von Briesen, Hagen, Geertsma, Eric R., Wilson, Ian A., Wernery, Ulrich, Koch-Nolte, Friedrich, Ward, Andrew B., Dietrich, Ursula
出版年 Sci Rep (2017)

Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies

著者: Bale, Shridhar, Martiné, Alexandra, Wilson, Richard, Behrens, Anna-Janina, Le Fourn, Valérie, de Val, Natalia, Sharma, Shailendra K., Tran, Karen, Torres, Jonathan L., Girod, Pierre-Alain, Ward, Andrew B., Crispin, Max, Wyatt, Richard T.
出版年 Front Immunol (2018)

Visualization of the HIV-1 Env glycan shield across scales

著者: Berndsen, Zachary T., Chakraborty, Srirupa, Wang, Xiaoning, Cottrell, Christopher A., Torres, Jonathan L., Diedrich, Jolene K., López, Cesar A., Yates, John R., van Gils, Marit J., Paulson, James C., Gnanakaran, Sandrasegaram, Ward, Andrew B.
出版年 Proc Natl Acad Sci U S A (2020)

Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein

著者: Pholcharee, Tossapol, Oyen, David, Torres, Jonathan L., Flores-Garcia, Yevel, Martin, Gregory M., González-Páez, Gonzalo E., Emerling, Daniel, Volkmuth, Wayne, Locke, Emily, King, C. Richter, Zavala, Fidel, Ward, Andrew B., Wilson, Ian A.
出版年 J Mol Biol (2020)

Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

著者: Yuan, Meng, Cottrell, Christopher A., Ozorowski, Gabriel, van Gils, Marit J., Kumar, Sonu, Wu, Nicholas C., Sarkar, Anita, Torres, Jonathan L., de Val, Natalia, Copps, Jeffrey, Moore, John P., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
出版年 Cell Host Microbe (2019)

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

著者: Wu, Nicholas C., Yuan, Meng, Liu, Hejun, Lee, Chang-Chun D., Zhu, Xueyong, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
出版年 bioRxiv (2020)

An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain

著者: Wu, Nicholas C., Yuan, Meng, Liu, Hejun, Lee, Chang-Chun D., Zhu, Xueyong, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
出版年 Cell Rep (2020)

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

著者: Liu, Hejun, Wu, Nicholas C., Yuan, Meng, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., van Schooten, Jelle, Zhu, Xueyong, Lee, Chang-Chun D., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
出版年 bioRxiv (2020)

Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity

著者: Liu, Hejun, Wu, Nicholas C., Yuan, Meng, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., van Schooten, Jelle, Zhu, Xueyong, Lee, Chang-Chun D., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
出版年 Immunity (2020)

Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein

著者: Oyen, David, Torres, Jonathan L., Aoto, Phillip C., Flores-Garcia, Yevel, Binter, Špela, Pholcharee, Tossapol, Carroll, Sean, Reponen, Sini, Wash, Rachael, Liang, Qi, Lemiale, Franck, Locke, Emily, Bradley, Allan, King, C. Richter, Emerling, Daniel, Kellam, Paul, Zavala, Fidel, Ward, Andrew B., Wilson, Ian A.
出版年 PLoS Pathog (2020)

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

著者: Bangaru, Sandhya, Ozorowski, Gabriel, Turner, Hannah L., Antanasijevic, Aleksandar, Huang, Deli, Wang, Xiaoning, Torres, Jonathan L., Diedrich, Jolene K., Tian, Jing-Hui, Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Yates, John R., Nemazee, David, Paulson, James C., Glenn, Greg, Smith, Gale, Ward, Andrew B.
出版年 bioRxiv (2020)

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

著者: Bangaru, Sandhya, Ozorowski, Gabriel, Turner, Hannah L., Antanasijevic, Aleksandar, Huang, Deli, Wang, Xiaoning, Torres, Jonathan L., Diedrich, Jolene K., Tian, Jing-Hui, Portnoff, Alyse D., Patel, Nita, Massare, Michael J., Yates, John R., Nemazee, David, Paulson, James C., Glenn, Greg, Smith, Gale, Ward, Andrew B.
出版年 Science (2020)