Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein

Lasting protection has long been a goal for malaria vaccines. The major surface antigen on Plasmodium falciparum sporozoites, the circumsporozoite protein (PfCSP), has been an attractive target for vaccine development and most protective antibodies studied to date interact with the central NANP repe...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Oyen, David, Torres, Jonathan L., Aoto, Phillip C., Flores-Garcia, Yevel, Binter, Špela, Pholcharee, Tossapol, Carroll, Sean, Reponen, Sini, Wash, Rachael, Liang, Qi, Lemiale, Franck, Locke, Emily, Bradley, Allan, King, C. Richter, Emerling, Daniel, Kellam, Paul, Zavala, Fidel, Ward, Andrew B., Wilson, Ian A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082059/
https://ncbi.nlm.nih.gov/pubmed/32150583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008373
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