DISTINCT ANTIBODY SPECIES: STRUCTURAL DIFFERENCES CREATING THERAPEUTIC OPPORTUNITIES

Por Muyldermans, Serge, Smider, Vaughn V.
Publicado no Curr Opin Immunol (2016)

Antibody Therapeutics in Oncology

Por Wold, Erik D, Smider, Vaughn V, Felding, Brunhilde H
Publicado no Immunotherapy (Los Angel) (2016)

Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies

Por Stanfield, Robyn L., Wilson, Ian A., Smider, Vaughn V.
Publicado no Sci Immunol (2016)

Mutagenesis and Evolution of Sulfated Antibodies using an Expanded Genetic Code

Por Liu, Chang C., Choe, Hyeryun, Farzan, Michael, Smider, Vaughn V., Schultz, Peter G.
Publicado em 2009

Antibody Microarrays Utilizing Site-Specific Antibody–Oligonucleotide Conjugates

Por Wold, Erik D., McBride, Ryan, Axup, Jun Y., Kazane, Stephanie A., Smider, Vaughn V.
Publicado no Bioconjug Chem (2015)

Functional Antibody CDR3 Fusion Proteins with Enhanced Pharmacological Properties

Por Zhang, Yong, Wang, Danling, de Lichtervelde, Lorenzo, Sun, Sophie B., Smider, Vaughn V., Schultz, Peter G., Wang, Feng
Publicado em 2013

Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR

Por Kazane, Stephanie A., Sok, Devin, Cho, Edward H., Uson, Maria Loressa, Kuhn, Peter, Schultz, Peter G., Smider, Vaughn V.
Publicado em 2012

Selective Formation of Covalent Protein Heterodimers with an Unnatural Amino Acid

Por Hutchins, Benjamin M., Kazane, Stephanie A., Staflin, Karin, Forsyth, Jane S., Felding-Habermann, Brunhilde, Smider, Vaughn V., Schultz, Peter G.
Publicado em 2011

Site-Specific Coupling and Sterically Controlled Formation of Multimeric Antibody Fab Fragments with Unnatural Amino Acids

Por Hutchins, Benjamin M., Kazane, Stephanie A., Staflin, Karin, Forsyth, Jane S., Felding-Habermann, Brunhilde, Schultz, Peter G., Smider, Vaughn V.
Publicado no J Mol Biol (2011)

The Evolution of Proteins with Genetically Encoded “Chemical Warheads”

Por Liu, Chang C., Mack, Antha V., Brustad, Eric M., Mills, Jeremy H., Groff, Dan, Smider, Vaughn V., Schultz, Peter G.
Publicado em 2009

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

Por Wang, Feng, Sen, Shiladitya, Zhang, Yong, Ahmad, Insha, Zhu, Xueyong, Wilson, Ian A., Smider, Vaughn V., Magliery, Thomas J., Schultz, Peter G.
Publicado em 2013

Synthesis of Bispecific Antibodies with Genetically Encoded Unnatural Amino Acids

Por Kim, Chan Hyuk, Axup, Jun Y., Dubrovska, Anna, Kazane, Stephanie A., Hutchins, Benjamin A., Wold, Erik D., Smider, Vaughn V., Schultz, Peter G.
Publicado no J Am Chem Soc (2012)

A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes

Por Furman, Jennifer L., Kang, Mingchao, Choi, Seihyun, Cao, Yu, Wold, Erik D., Sun, Sophie B., Smider, Vaughn V., Schultz, Peter G., Kim, Chan Hyuk
Publicado no J Am Chem Soc (2014)

Protein evolution with an expanded genetic code

Por Liu, Chang C., Mack, Antha V., Tsao, Meng-Lin, Mills, Jeremy H., Lee, Hyun Soo, Choe, Hyeryun, Farzan, Michael, Schultz, Peter G., Smider, Vaughn V.
Publicado em 2008

Self-Assembled Antibody Multimers through Peptide Nucleic Acid Conjugation

Por Kazane, Stephanie A., Axup, Jun Y, Kim, Chan Hyuk, Ciobanu, Mihai, Wold, Erik D., Barluenga, Sofia, Hutchins, Benjamin A., Schultz, Peter G., Winssinger, Nicolas, Smider, Vaughn V.
Publicado em 2012

Immunochemical termination of self-tolerance

Por Grünewald, Jan, Tsao, Meng-Lin, Perera, Roshan, Dong, Liqun, Niessen, Frank, Wen, Ben G., Kubitz, Diane M., Smider, Vaughn V., Ruf, Wolfram, Nasoff, Marc, Lerner, Richard A., Schultz, Peter G.
Publicado em 2008

Reshaping Antibody Diversity

Por Wang, Feng, Ekiert, Damian C., Ahmad, Insha, Yu, Wenli, Zhang, Yong, Bazirgan, Omar, Torkamani, Ali, Raudsepp, Terje, Mwangi, Waithaka, Criscitiello, Michael F., Wilson, Ian A., Schultz, Peter G., Smider, Vaughn V.
Publicado em 2013

Bispecific small molecule–antibody conjugate targeting prostate cancer

Por Kim, Chan Hyuk, Axup, Jun Y., Lawson, Brian R., Yun, Hwayoung, Tardif, Virginie, Choi, Sei Hyun, Zhou, Quan, Dubrovska, Anna, Biroc, Sandra L., Marsden, Robin, Pinstaff, Jason, Smider, Vaughn V., Schultz, Peter G.
Publicado em 2013

Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids

Por Grünewald, Jan, Hunt, Grady S., Dong, Liqun, Niessen, Frank, Wen, Ben G., Tsao, Meng-Lin, Perera, Roshan, Kang, Mingchao, Laffitte, Bryan A., Azarian, Sassan, Ruf, Wolfram, Nasoff, Marc, Lerner, Richard A., Schultz, Peter G., Smider, Vaughn V.
Publicado em 2009

Synthesis of site-specific antibody-drug conjugates using unnatural amino acids

Por Axup, Jun Y., Bajjuri, Krishna M., Ritland, Melissa, Hutchins, Benjamin M., Kim, Chan Hyuk, Kazane, Stephanie A., Halder, Rajkumar, Forsyth, Jane S., Santidrian, Antonio F., Stafin, Karin, Lu, Yingchun, Tran, Hon, Seller, Aaron J., Biroc, Sandra L., Szydlik, Aga, Pinkstaff, Jason K., Tian, Feng, Sinha, Subhash C., Felding-Habermann, Brunhilde, Smider, Vaughn V., Schultz, Peter G.
Publicado em 2012