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Protein evolution with an expanded genetic code
We have devised a phage display system in which an expanded genetic code is available for directed evolution. This system allows selection to yield proteins containing unnatural amino acids should such sequences functionally outperform ones containing only the 20 canonical amino acids. We have optim...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584696/ https://ncbi.nlm.nih.gov/pubmed/19004806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809543105 |
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