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The Evolution of Proteins with Genetically Encoded “Chemical Warheads”
[Image: see text] We recently developed a phage-based system for the evolution of proteins in bacteria with expanded amino acid genetic codes. Here, we demonstrate that the unnatural amino acid p-boronophenylalanine (BF) confers a selective advantage in the evolution of glycan binding proteins. We s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745334/ https://ncbi.nlm.nih.gov/pubmed/19555063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902985e |
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