Exploring the potential impact of an expanded genetic code on protein function

With few exceptions, all living organisms encode the same 20 canonical amino acids; however, it remains an open question whether organisms with additional amino acids beyond the common 20 might have an evolutionary advantage. Here, we begin to test that notion by making a large library of mutant enz...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Xiao, Han, Nasertorabi, Fariborz, Choi, Sei-hyun, Han, Gye Won, Reed, Sean A., Stevens, Raymond C., Schultz, Peter G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460475/
https://ncbi.nlm.nih.gov/pubmed/26038548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507741112
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