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Expanding the genetic code of Mus musculus
Here we report the expansion of the genetic code of Mus musculus with various unnatural amino acids including N(ɛ)-acetyl-lysine. Stable integration of transgenes encoding an engineered N(ɛ)-acetyl-lysyl-tRNA synthetase (AcKRS)/tRNA(Pyl) pair into the mouse genome enables site-specific incorporation...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321798/ https://ncbi.nlm.nih.gov/pubmed/28220771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14568 |
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