Expanding the Genetic Code of Escherichia coli with Phosphoserine

O -Phosphoserine (Sep), the most abundant phosphoamino acid in the eukaryotic phosphoproteome, is not encoded in the genetic code, but synthesized posttranslationally. Here, we present an engineered system for specific cotranslational Sep incorporation (directed by UAG) into any desired position in...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Park, Hee-Sung, Hohn, Michael J., Umehara, Takuya, Guo, Li-Tao, Osborne, Edith M., Benner, Jack, Noren, Christopher J., Rinehart, Jesse, Söll, Dieter
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547737/
https://ncbi.nlm.nih.gov/pubmed/21868676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1207203
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