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Expanding the Genetic Code of Escherichia coli with Phosphoserine

O -Phosphoserine (Sep), the most abundant phosphoamino acid in the eukaryotic phosphoproteome, is not encoded in the genetic code, but synthesized posttranslationally. Here, we present an engineered system for specific cotranslational Sep incorporation (directed by UAG) into any desired position in...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Park, Hee-Sung, Hohn, Michael J., Umehara, Takuya, Guo, Li-Tao, Osborne, Edith M., Benner, Jack, Noren, Christopher J., Rinehart, Jesse, Söll, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547737/
https://ncbi.nlm.nih.gov/pubmed/21868676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1207203
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