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Expanding the Genetic Code of Escherichia coli with Phosphoserine

O -Phosphoserine (Sep), the most abundant phosphoamino acid in the eukaryotic phosphoproteome, is not encoded in the genetic code, but synthesized posttranslationally. Here, we present an engineered system for specific cotranslational Sep incorporation (directed by UAG) into any desired position in...

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Pubblicato in:Science
Autori principali: Park, Hee-Sung, Hohn, Michael J., Umehara, Takuya, Guo, Li-Tao, Osborne, Edith M., Benner, Jack, Noren, Christopher J., Rinehart, Jesse, Söll, Dieter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547737/
https://ncbi.nlm.nih.gov/pubmed/21868676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1207203
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