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Self-Assembled Antibody Multimers through Peptide Nucleic Acid Conjugation
With the recent clinical success of bispecific antibodies, a strategy to rapidly synthesize and evaluate bispecific or higher order multispecific molecules could facilitate the discovery of new therapeutic agents. Here we show that unnatural amino acids (UAAs) with orthogonal chemical reactivity can...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951380/ https://ncbi.nlm.nih.gov/pubmed/23210862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja309505c |
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