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Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold

Delivery to intracellular target sites is still one of the main obstacles in the development of peptide nucleic acids (PNAs) as antisense-antigene therapeutics. Here, we designed a self-assembled oligonucleotide scaffold that included a central complementary region for self-assembly and lateral regi...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zhao, Xing-Liang, Chen, Bi-Cheng, Han, Jin-Chao, Wei, Lai, Pan, Xiao-Ben
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661726/
https://ncbi.nlm.nih.gov/pubmed/26612536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17640
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