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Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold

Delivery to intracellular target sites is still one of the main obstacles in the development of peptide nucleic acids (PNAs) as antisense-antigene therapeutics. Here, we designed a self-assembled oligonucleotide scaffold that included a central complementary region for self-assembly and lateral regi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhao, Xing-Liang, Chen, Bi-Cheng, Han, Jin-Chao, Wei, Lai, Pan, Xiao-Ben
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661726/
https://ncbi.nlm.nih.gov/pubmed/26612536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17640
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