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Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold

Delivery to intracellular target sites is still one of the main obstacles in the development of peptide nucleic acids (PNAs) as antisense-antigene therapeutics. Here, we designed a self-assembled oligonucleotide scaffold that included a central complementary region for self-assembly and lateral regi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Zhao, Xing-Liang, Chen, Bi-Cheng, Han, Jin-Chao, Wei, Lai, Pan, Xiao-Ben
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661726/
https://ncbi.nlm.nih.gov/pubmed/26612536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17640
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