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Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies
A subset of bovine antibodies have an exceptionally long third heavy-chain complementarity determining region (CDR H3) that is highly variable in sequence and includes multiple cysteines. These long CDR H3s (up to 69 residues) fold into a long stalk atop which sits a knob domain that is located far...
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Publicado no: | Sci Immunol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5000368/ https://ncbi.nlm.nih.gov/pubmed/27574710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaf7962 |
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