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Diversity in the Cow Ultralong CDR H3 Antibody Repertoire
Typical antibodies found in humans and mice usually have short CDR H3s and generally flat binding surfaces. However, cows possess a subset of antibodies with ultralong CDR H3s that can range up to 70 amino acids and form a unique “stalk and knob” structure, with the knob protruding far out of the an...
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| Veröffentlicht in: | Front Immunol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5994613/ https://ncbi.nlm.nih.gov/pubmed/29915599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01262 |
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