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Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR

Antibody conjugates are widely used as diagnostics and imaging reagents. However, many such conjugates suffer losses in sensitivity and specificity due to nonspecific labeling techniques. We have developed methodology to site-specifically conjugate oligonucleotides to antibodies containing a genetic...

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Detalhes bibliográficos
Main Authors: Kazane, Stephanie A., Sok, Devin, Cho, Edward H., Uson, Maria Loressa, Kuhn, Peter, Schultz, Peter G., Smider, Vaughn V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309776/
https://ncbi.nlm.nih.gov/pubmed/22345566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120682109
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