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Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR

Antibody conjugates are widely used as diagnostics and imaging reagents. However, many such conjugates suffer losses in sensitivity and specificity due to nonspecific labeling techniques. We have developed methodology to site-specifically conjugate oligonucleotides to antibodies containing a genetic...

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Autores principales: Kazane, Stephanie A., Sok, Devin, Cho, Edward H., Uson, Maria Loressa, Kuhn, Peter, Schultz, Peter G., Smider, Vaughn V.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309776/
https://ncbi.nlm.nih.gov/pubmed/22345566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120682109
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