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Site-specific Antibody-polymer Conjugates for siRNA Delivery
We describe here the development of site-specific antibody-polymer conjugates (APCs) for the selective delivery of small interference RNAs (siRNAs) to target cells. APCs were synthesized in good yields by conjugating an aminooxy-derivatized cationic block copolymer to an anti-HER2 Fab or full length...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3955097/ https://ncbi.nlm.nih.gov/pubmed/23924037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4059525 |
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