Lyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery

INTRODUCTION: Long-term stability of therapeutic candidates is necessary toward their clinical applications. For most nanoparticle systems formulated in aqueous solutions, lyophilization or freeze-drying is a common method to ensure long-term stability. While lyophilization of lipid, polymeric, or i...

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Библиографические подробности
Опубликовано в: :Int J Nanomedicine
Главные авторы: Ngamcherdtrakul, Worapol, Sangvanich, Thanapon, Reda, Moataz, Gu, Shenda, Bejan, Daniel, Yantasee, Wassana
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045907/
https://ncbi.nlm.nih.gov/pubmed/30022824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S164393
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