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Targeted treatment of metastatic breast cancer by PLK1 siRNA delivered by an antioxidant nanoparticle platform

Metastatic breast cancer is developed in about 20–30% of newly diagnosed early stage breast cancer patients despite treatments. Herein, we report a novel nanoparticle platform with intrinsic anti-metastatic properties for the targeted delivery of Polo-like kinase 1 siRNA (siPLK1). We first evaluated...

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Foilsithe in:Mol Cancer Ther
Main Authors: Morry, Jingga, Ngamcherdtrakul, Worapol, Gu, Shenda, Reda, Moataz, Castro, David J., Sangvanich, Thanapon, Gray, Joe W., Yantasee, Wassana
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445934/
https://ncbi.nlm.nih.gov/pubmed/28138033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0644
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