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Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted SiRNA Delivery to HER2+ Breast Cancer

In vivo delivery of siRNAs designed to inhibit genes important in cancer and other diseases continues to be an important biomedical goal. We now describe a new nanoparticle construct that has been engineered for efficient delivery of siRNA to tumors. The construct is comprised of a 47-nm mesoporous...

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Detalhes bibliográficos
Publicado no:Adv Funct Mater
Main Authors: Ngamcherdtrakul, Worapol, Morry, Jingga, Gu, Shenda, Castro, David J., Goodyear, Shaun M., Sangvanich, Thanapon, Reda, Moataz M., Lee, Richard, Mihelic, Samuel A., Beckman, Brandon L., Hu, Zhi, Gray, Joe W., Yantasee, Wassana
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469082/
https://ncbi.nlm.nih.gov/pubmed/26097445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201404629
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