טוען...
Site-Specific Coupling and Sterically Controlled Formation of Multimeric Antibody Fab Fragments with Unnatural Amino Acids
Immunoconjugates and multispecific antibodies are rapidly emerging as highly potent experimental therapeutics against cancer. We have developed a method to incorporate an unnatural amino acid, p-acetylphenylalanine (pAcPhe) into an antibody antigen binding fragment (Fab) targeting HER2 (human epider...
שמור ב:
| הוצא לאור ב: | J Mol Biol |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4278757/ https://ncbi.nlm.nih.gov/pubmed/21237172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.01.011 |
| תגים: |
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