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Activation of tumor cell integrin α(v)β(3) controls angiogenesis and metastatic growth in the brain

The incidence of brain metastasis is rising and poses a severe clinical problem, as we lack effective therapies and knowledge of mechanisms that control metastatic growth in the brain. Here we demonstrate a crucial role for high-affinity tumor cell integrin α(v)β(3) in brain metastatic growth and re...

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Detalhes bibliográficos
Main Authors: Lorger, Mihaela, Krueger, Joseph S., O'Neal, Melissa, Staflin, Karin, Felding-Habermann, Brunhilde
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697113/
https://ncbi.nlm.nih.gov/pubmed/19541645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903035106
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