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DISTINCT ANTIBODY SPECIES: STRUCTURAL DIFFERENCES CREATING THERAPEUTIC OPPORTUNITIES

Antibodies have been a remarkably successful class of molecules for binding a large number of antigens in therapeutic, diagnostic, and research applications. Typical antibodies derived from mouse or human sources use the surface formed by complementarity determining regions (CDRs) on the variable re...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Muyldermans, Serge, Smider, Vaughn V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884505/
https://ncbi.nlm.nih.gov/pubmed/26922135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.02.003
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