Open and Closed Structures Reveal Allostery and Pliability in the HIV-1 Envelope Spike

For many enveloped viruses, binding to a receptor(s) on a host cell acts as a first step in a series of events culminating in fusion with the host cell membrane and transfer of genetic material for replication [for review see(1,2)]. The envelope glycoprotein (Env) trimer on the surface of HIV is res...

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Publicado en:Nature
Autores principales: Ozorowski, Gabriel, Pallesen, Jesper, de Val, Natalia, Lyumkis, Dmitry, Cottrell, Christopher A., Torres, Jonathan L., Copps, Jeffrey, Stanfield, Robyn L., Cupo, Albert, Pugach, Pavel, Moore, John P., Wilson, Ian A., Ward, Andrew B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538736/
https://ncbi.nlm.nih.gov/pubmed/28700571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23010
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